摘要
Two chiral stationary phases(BCDs and YBCDs) were prepared by bonding β-cyclodextrin derivative with α-Schiff base group from β-cyclodextrin monoaldehyde to the sillica gel via 3-glyci-{dyloxypropyltrimethoxysilane} as a coupling agent. Using acetonitrile-TEAA as mobile phase, good enantiomeric resolutions were obtained for DL-aminoacide on BCDs and YBCDs, including Leucine, Threonine and Valine. It is also observed that the higher separation factor of threonine was at pH {7.11} for both of the column, and the optimal column temperatures of Leucine appeared at 30 ℃ or {40 ℃}, respectively for YBCDs and BCDs.
Two chiral stationary phases （BCDs and YBCDs） were prepared by bonding β-cyclodextrin derivative with α-Schiff base group from β-cyclodextrin monoaldehyde to the sillica gel via 3-glycidyloxypropyltrimethoxysilane as a coupling agent. Using acetonitrile-TEAA as mobile phase, good enantiomeric resolutions were obtained for DL-aminoacide on BCDs and YBCDs, including Leucine, Threonine and Valine. It is also observed that the higher separation factor of threonine was at pH 7. 11 for both of the column, and the optimal column temperatures of Leucine appeared at 30℃ or 40℃, respectively for YBCDs and BCDs.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2005年第8期1443-1445,共3页
Chemical Journal of Chinese Universities
基金
北京理工大学基础研究基金重点项目(批准号:000Y05)资助.
