消毒剂杀灭溶血性链球菌试验效果观察

Observation on germicidal efficacy of disinfectants to Hemolytic streptococci

目的:观察消毒剂杀灭溶血性链球菌试验效果。方法:试验采用悬液定量杀菌试验方法,选择4种常用消毒剂:次氯酸钠、过氧乙酸、洗必泰和碘伏分别进行悬液定量杀灭溶血性链球菌试验。结果:次氯酸钠有效氯含量200mg/L、过氧乙酸含量为150mg/L、洗必泰含量为2000mg/L、碘伏有效碘含量200mg/L时,作用3min对溶血性链球菌的杀灭对数值大于5;次氯酸钠有效氯含量250mg/L、过氧乙酸含量为100mg/L、洗必泰含量为2500mg/L、碘伏有效碘含量250mg/L时,作用3min对大肠杆菌的杀灭对数值大于5。结论:次氯酸钠、过氧乙酸、洗必泰、碘伏4种消毒剂均可用于杀灭溶血性链球菌;溶血性链球菌对消毒剂的抗力低于大肠杆菌。

Objective ： To observe the germicidal efficacy of disinfectants to Hemolytic streptococci. Methods ： The method of liquid quantitative germicidal test was used. Four kinds of disinfectants were used in this study ： sodium hypochlorite, peracetic acid,chlorhexidine and iodophor. Results： When the end available chlorine concentration of sodium hypochlorite was 200 mg/L, the end concentration of peracetic acid was 150 mg/L, the end concentration of chlorhexidine was 2 000 mg,/L,the end available iodine concentration of iodophor was 200 mg/L, with 3 - minute contact time, the average killing rate to Hemolytic streptococci was greater than 5 logl0 reduction. When the end available chlorine concentration of sodium hypochlorite was 250 mg/L,the end concentration of peracetic acid was 100 mg/L, the end concentration of chlorhexidine was 2 500 mg/L,the end available iodine concentration of iodophor was 250 mg/L, with 3 - minute contact time, the average killing rate to Escherichia coli was greater than 5 logl0 reduction. Conclusion：Four kinds of disinfectants used in this study： sodium hypochlorite, peracetic acid, chlorhexidine and iodophor are all suitable for disinfection to Hemolytic streptococci. Hemolytic streptococci is more sensitive to disinfectants than Escherichia coli.