改进侧脑室穿刺引流术治疗结核性脑膜炎临床观察

An Clinical Observation on the Improved Puncture Drainage of Lateral Ventricle for Treating Tuberculous Meningitis

目的寻找结核性脑膜炎颅内高压有效的治疗方法。方法216例结核性脑膜炎颅内高压患者分别以改进法(实验组)、传统法(对照组)行侧脑室穿刺引流术,比较术后患者临床表现、颅内压水平、脑脊液性状、脑脊液外渗及颅内感染情况及患者存活率。结果两组在颅内压恢复正常例数、脑脊液恢复正常时间、脑脊液外渗、颅内感染及意外情况等方面差异有显著性(P<0·05);但在存活率等方面差异无显著性(P>0·05)。结论改进侧脑室穿刺引流术治疗结核性脑膜炎优于传统法,值得推广。

Objective To explore the effective method on treating intracranial hypertension in patients with tuberculous meningitis. Melhods 216 cases of patients with intracranial hypertension of tuberculous meningitis were divided into experimental group and control group, which were treated by using the improved and traditional puncture drainage of lateral ventricle, respectively. The postoperative clinical manifestation, intracranial pressure, cercbrospinal fluid parameters, intracranial infection, the exosmosis of cercbrospinal fluid, and the survival rates of patients were compared between the two groups. Results There were significant differences in the dechnirlg speed of intracranial pressure, the time of cerebrospinal fluid getting back to normality, the frequency of intracranial infection, cerebrospinal fluid exosmosis and the unexpected events between the two groups, but there was no significant difference in the patients survival rate between the two groups（ P 〉 0.05）. Conclusion The improved puncture drainage of lateral ventricle for treating tuberculous meningitis was better than the traditional one, and was worthy of popularization.