山东菏泽布—加综合征病人尿碘水平的测定

Study on the relation between the Budd-Chiari syndrome and urine iodine in Heze area of Shandong Province

目的了解布—加综合征(Budd-ChiariSyndrome,BCS)病人尿碘水平,探讨碘在其发病中的作用。方法选择58例BCS患者和50例正常人对尿碘进行检测和分析。结果BCS患者中尿碘水平(371.28±40.79)μg/L明显高于正常对照组(232.20±39.27)μg/L,P<0.01,但男、女尿碘均值无明显差异。正常健康对照组男、女尿碘均值无明显差异。结论BCS的发生可能与高碘相关,碘在BCS的发病机制中的作用是值得进行深入研究的课题。

To study the relations between Budd - Chiari syndrome（BCS）and urine iodine so as to understand the pathogenesis of BCS. Method Urinary iodine determination on 58 BCS patients and 50 healthy persons by As - Ce catalytic spectrophotometery. Results The mean value of the BCS patient group was （371.28 ± 40.79） μg/L while that of the control group （232.20 ±39.27） μg/L, there existsed a significant difference（ p 〈 0.01 ）. Conclusion Budd- Chiari syndrome pathogenesis is maybe related to high content of Iodine.Iodine is potentially toxic factor in the pathogenesis of Budd - Chiari syndrome.