抽动障碍患者血清锌测定及意义

Detection of serum zinc and its significances in children with tic disorders

目的了解抽动障碍(ticdisorders)患者血清锌水平并探讨血清锌测定的意义。方法测定19例抽动障碍患者(病例组)空腹血清锌浓度,并与20例正常儿童(对照组)进行比较。结果病例组血清锌为(12·04±1·07)μmol/L,对照组为(13·21±1·13)μmol/L,两组血清锌均值比较,差异有显著意义(P<0·01)。结论抽动障碍患者存在低血锌,推测低锌与抽动障碍的发病机制有关,治疗时应予考虑。

Objective To study the change of serum level of zinc and its significances in children with tic disorders. Methods Serum zinc of 19 cases with tic disorders（case group） and 20 normal children（control group） were detected by Hitachi 7170A automatic analyzer, Result The serum level of zinc of case group was （12.04±1.07）μmol/L while that of control group was （13.21±1.13）μmol/L. The former was significantly lower than the latter （P〈0.01）. Conclusion Low serum level of zinc may accompany with tic disorders in children. We suspect that zinc deficiency is correlated with tic disorders in pathogenesis. It is necessary to detect the serum level of zinc while treating with patients with tic disorders.