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血清胆红素和尿酸与缺血性心脏病的相关性研究

Study on the correlation between serum bilirubin and uric acid and ischemic heart disease
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摘要 目的:探讨血清胆红素及尿酸与缺血性心脏病的关系。方法:测定158例缺血性心脏病患者(实验组)及132例健康者(对照组)血清总胆红素、直接胆红素、间接胆红素和尿酸的含量。结果:实验组尿酸含量较对照组明显升高(P<0.01),总胆红素、直接胆红素和间接胆红素含量明显低于对照组(P<0.01)。结论:血清胆红素和尿酸水平的变化对缺血性心脏病的诊断及病情变化监测具有重要的临床意义。 Objective To investigate the relationship between serum bilirubin and uric acid and ischemic heart disease. Methods The serum levels of bilirubin and uric acid were determined in 158 patients with ischemic heart disease (experiment group) and in 132 healthy subjects (control group). Results The serum levels of uric acid in experiment group were markedly higher than those in control group (P〈0.01). The serum levels of TBIL, DBIL and IBIL in experiment group were markedly lower than those in control group (P〈0.01) . Conclusion The change in serum bilirubin and uric acid is of important clinical significance in the diagnosis and monitoring of the ischemic heart disease.
出处 《实用诊断与治疗杂志》 2005年第8期560-560,563,共2页 Journal of Practical Diagnosis and Therapy
关键词 缺血性心脏病 胆红素 尿酸 Ischemic heart disease bilirubin uric acid
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参考文献5

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  • 2Hunt S, Kronenberg F, John H, et al. Association of plasma bilirubin with coronary heart disease and segregation of bilirubin as a major gene trait: thenhlbi family heart study [ J ].Atherosclerosis, 2001, 154(3) :747.
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  • 4France L, Pahor M, Dibari M, et al. Serum uric acid, diuretic treatment and risk of cardiovascular events in the systolic hypertension in the elderly program (SHEP) [J]. J Hypertens,2000, 18:1149.
  • 5Bickel C, Ruppredat H, Blankenberg S. Serum uric acid as an independent predictor of mortality in patie nts with angiographically proven coronary artery disease [J]. Am J Cardiol, 2002 , 89 (1):12.

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