4种小鼠的寒、热体质研究

Study of cold or hot constitution in four species of mice

目的研究4种品系小鼠的寒、热体质。方法8～9周龄昆明、BALB/c、C57BL/6J、ICR小鼠,以及4～5周龄昆明小鼠,同步系统检测其生物学特性,然后以统一的评价标准评价4种品系小鼠的寒、热体质。并对BALB/c小鼠给予参桂理中丸和利血平做药物反证。结果①4～5周龄昆明小鼠与8～9周龄昆明小鼠比较体质明显偏热;②BALB/c小鼠与C57BL/6J小鼠比较体质偏寒;③8～9周龄雄性BALB/c小鼠、雄性和雌性C57BL/6J小鼠与8～9周龄相应性别昆明小鼠比较体质无明显差异;8～9周龄雌性BALB/c小鼠与8～9周龄雌性昆明小鼠比较体质偏寒;④8～9周龄ICR小鼠与8～9周龄BALB/c小鼠、C57BL/6J小鼠比较体质偏热;8～9周龄雄性ICR小鼠与8～9周龄雄性昆明小鼠比较体质偏热。结论4种品系小鼠存在寒、热体质差异。

Objective It is to study the cold or hot constitution in four species of mice. Methods Simultaneous systematic inspection about biological characteristics of eight to nine week-old Kunming mice, BALB/c mice, C57BL/6Jmice and ICR mice and four to five week-old Kunming mice were taken, and their cold or hot constitution were assessed with a same criterion. At the same time BALB/c mice were taken drug counterevidence with Shenguilizhong pill and Reserpine. Results ①The constitutions of four to five week-old Kunming mice were more obviously prone to hot compared with eight to nine week-old ones. ②The constitutions of BALB/c mice were prone to cold compared with C57BL/6J mice. ③There was no significant difference in constitution between eight to nine week-old male BALB/c mice and C57BL/6J mice （include male and female）and the same age corresponding sex Kunming mice. The constitutions of eight to nine week-old female BALB/c mice were prone to cold compared with the same age corresponding sex Kunming mice. ④The constitutions of eight to nine week-old ICR mice were prone to hot compared with the same age BALB/c mice and C57BL/6J mice. The constitutions of eight to nine week-old male ICR mice were prone to hot compared with the same age corresponding sex Kunming mice. Conclusion Four species of mice have different cold or hot constitutions.