肝硬化患者红细胞及血小板相关参数测定及临床意义

Determination of interrelated parameters of red blood cells and blood platelets of cirrhosis sufferers and its clinic significance

目的探讨肝硬化患者红细胞平均体积(MCV)、红细胞体积分布宽度(RDW)及血小板参数变化与病情关系的临床意义。方法应用NIHONKOHDEN-6138K型全自动血液分析仪,检测43例肝硬化患者平均红细胞体积(MCV)、红细胞体积分布宽度(RDW)、血小板计数(PLT)、平均血小板体积(MPV)、血小板压积(PCT)及血小板分布宽度(PDW)。结果(1)肝硬化患者MCV、RDW、PDW显著高于对照组(P<0.01),PLT、MPV、PCT显著低于对照组(P<0.01)。(2)MCV、RDW之间呈正相关,PLT、MPV与PCT呈正相关,PLT、MPV与PDW呈负相关。结论肝硬化患者MCV、RDW及血小板参数的测定,对初步评估肝硬化患者肝功能损害程度和判断有无出血倾向具有重要意义。

Objective To study the clinic significance of the relationship between patients conditions and MCV, RDW and changes in platelets parameters of cirrhosis sufferers. Methods The research work was done by using automatic blood-analysing machines（Model NIHONKOHDEK-6318K）to exame MCV,RDW, PLT, MPV, PCT and PDW of 43 cases of cirrhosis. Results （1）MCV, RDW and PDW were evidently higher than the compared group（P＜0.01）, PLT, MPV and PCT were evidently lower than the compared group（P＜0.01 ）. （2）The interrelation between MCV and RDW was positively correlated,PLT, MPV and PCT were positively correlated and PLT, MPV and PDW were negatively correlated. Conclusions It is very significant to determine the parameters of MCV, RDW and blood platelets of cirrhosis sufferers on preliminarily evaluating the degree of impairment of liver function and judging the inclination to liver hemorrhage.