摘要
目的探讨硫普罗宁(商品名凯西莱)对肝癌介入治疗后不良反应的防治作用。方法62例原发性肝细胞癌患者分为观察组和对照组。经肝动脉化疗栓塞治疗(TACE)后,观察二组肝功能变化和白细胞减少的不良反应发生情况。结果治疗后二组的肝功能的变化和白细胞减少差异有统计学意义,对肝功能损害的治疗总有效率分别为90%、63%,二组比较差异有统计学意义(P<0.05)。结论硫普罗宁对肝癌介入治疗后不良反应有较好的防治作用。
Objective To explore the protective function of Tiopronin on side effects in patients with hepatocellular carcinoma after interventional therapy. Methods 62 cases with primary hepatocellular carcinoma were divided into two groups, Tiopronin treated group and control group, which were administered with transcatheter hepatic arterial chemoembolization（TACE）. It were observed respectively that the changes of liver function and leukocytopenia on side effects in two groups. Results There was significant difference in side effects between the two groups. It were separately 90%, 63% , and the total effective rates of treating the impairment of liver function after TACE in the treated and the control group showed significant difference （P〈0.05）. Conclusion Tiopronin is effective for prevention and treatment on side effects in patients with hepatocellular carcinoma after interventional therapy.
出处
《中国煤炭工业医学杂志》
2005年第9期955-956,共2页
Chinese Journal of Coal Industry Medicine
关键词
硫普罗宁
肝癌
介入治疗
不良反应
Tiopronin
hepatocellular carcinoma
interventional therapy
side effect
