异体松质骨植骨治疗成人单腔骨囊肿的长期随访

A LONG-TERM FOLLOW-UP OF TREATMENT OF ADULT UNICAMERAL BONE CYSTS WITH ALLOGRAFT OF LYOPHILIZED CANCELLOUS BONE

目的回顾异体松质骨植骨治疗成人单腔骨囊肿的自然转归和远期临床效果。方法1993年～1998年,采用异体冷冻干燥松质骨治疗15例成人单腔骨囊肿,其中男5例,女10例,年龄19～41岁,平均27岁。随访期间不同时期门诊复查,常规摄X线平片或X线断层片及CT扫描检查。结果本组获随访6～11年,平均7.5年。X线片示,术后早期植入的松质骨粒呈颗粒状,界限清楚;术后2～3个月,松质骨粒边界变得模糊不清;术后5个月,骨粒开始相互融合,形成片状,密度增加;术后7个月,植入骨粒完全融合;此后至随访结束时,再生骨存在骨重建,所有患者未见囊肿复发。CT扫描更加清晰地显示松质骨粒被新骨替代的过程。随访结束时,所有患者疼痛消失或明显改善。结论采用异体冷冻干燥松质骨治疗成人单腔骨囊肿,经长期随访观察,能够获得良好效果。

Objective To investigate the long term clinical results of treatment of adult unicameral bone cyst with cancellous allograft. Methods From 1993 to 1998, 15 patients with unicameral bone cyst were treated by allograft with lyophilized cancellous bone. Among 15 patients, there were 5 males and 10 females, aging 19-41 years with an average of 27 years. The average follow-up time was 7.5 years （6-11 years）. The X-ray films were taken and the CT scanning were carried out. Results The X-ray films showed that the aliograft particles became vague 2-3 months after operation, that the allograft particles fused and began to form new bone and the bone density increased 5 months after operation, and that new bone formation completed after 7 months of operation. At the end of follow-up, remodelling in new bone occurred. Reoccurrence was not found in all patients. The symptom of pain disappeared or relieved obviously. Conclusion Allograft of lyophilized cancellous bone is an effective treatment for adult unicameral bone cysts.