肥胖儿童血液流变学检测的临床意义

The clinical significance of the detection of blood rheology in obese children

目的探讨肥胖症儿童血液流变学变化及其临床意义。方法100例小儿肥胖症儿童分成二组,其中无高血脂组74人和高血脂组26人,并以30例正常健康儿童作为对照组,各组肝肾功能均正常。取静脉血EDTA抗凝,用PLS-F200B型全自动血液流变测量仪按仪器说明书测定血液流变学指标。同时用VITROS-950生化分析仪检测血脂成份。结果小儿肥胖症儿童高血脂组全血粘度(高、中、低切)、血浆粘度、红细胞压积(Hct)、红细胞聚集指数、红细胞刚性指数均明显高于对照组,且差异显著(P<0.01),无高血脂组上述指标虽较高血脂组显著下降(P<0.01),但仍明显高于对照组(P<0.01)。结论高血脂和无高血脂的肥胖症儿童均存在血液高凝、高粘滞状态。

Objective To discuss the clinical significance of the detection of blood rheology change in obese children. Methods 100 obese children were divided into two groups, 74 of them without hyperlipemia, 26 with hyperlipemia. There were 30 healthy children as the normal control. The hepatorenal functions of all the children were norreal. Their blood specimens with anticoagnlarit EDTA for the detection of blood rheology by the instrument PI^-F200B and the ingredient of the blood-fat was examined by the VITROS-950 biochemistry analyzer. Results The blood viscosity,plasma viscosity,hematocrit,the aggregative and rigid index of the red blood cell in the obese children with hypedipemiawere obvious elevation than the control group, and were of great significance （ P 〈 0.01 ）. In the non-hyperlipemia group, all above indexes were less than hyperlipemia,but higher than control group and had significance of difference（ P 〈0. 01 ）.Conclusion There were high blood agglutination and hyperviscosity in obese children.