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葛根素对脓毒症大鼠凝血分子标志物水平的影响 被引量:2

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摘要 目的:观察脓毒症大鼠血浆凝血分子标志物凝血酶原片段1+2(F1+2)、D-二聚体(DD)、凝血酶调节蛋白(TM)和P-选择素(Ps)的变化及葛根素(Puerarin,Pue)对该变化的影响. 方法:60只动物随机分为正常对照组、假手术组、脓毒症组和葛根素治疗组,采用盲肠结扎穿孔(CLP)术复制脓毒症模型;分别于CLP后2、8、16小时尾静脉采血,ELISA法检测血浆F1+2、DD、TM和Ps含量的改变.
作者 袁修学
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2005年第8期1662-1662,共1页 Chinese Journal of Pathophysiology
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同被引文献6

  • 1ZHONG-HUA LIU,RAN WEI,YA-PING WU,TON LISMAN,ZENG-XIAN WANG,JI-JU HAN,DAO-LING REN,BIN CHEN,ZUO-LI XIA,BIAO CHEN,ZHEN ZHU,YAN ZHANG,XING CUI,HAI-TAO HU,PHILIP G. DE GROOT,WEN-BO XU.Elevated Plasma Tissue-type Plasminogen Activator (t-PA) and Soluble Throm-bomodulin in Patients Suffering From Severe Acute Respiratory Syndrome (SARS) as a Possible Index for Prognosis and Treatment Strategy[J].Biomedical and Environmental Sciences,2005,18(4):260-264. 被引量:2
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  • 4丁新,盛宏光,龚家雷.凝血酶调节蛋白在糖尿病肾病中的关系探讨.中华新医学,2004,5(13):1171-1172.
  • 5Cobankara U,Ozatli D,Kiraz S,et al.Successful treatment of rheumatoid arthritis is associated with a reduction in serum sE-selectin and thrombomodulin level[J].Clin Rheumatol,2004,23 (5):430-434.
  • 6Macgregor IR,Perrie AM,Donnelly SC,et al.Modulation of human endothelial thrombomodulin by neutrophils and their release products[J].Am J Respir Crit Care Med,1997,155(1):47 -52.

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