原发性高血压合并糖尿病自主神经活性变化

The change rule of autonomic nerve in primary hypertension whit diabetes

目的:探讨原发性高血压合并糖尿病患者自主神经变化规律。方法:对37例原发性高血压合并糖尿病患者进行24小时心率变异时域分析,并与年龄匹配的单纯性原发性高血压患者及对照组比较,观察心率变化规律。结果:单纯性原发性高血压病组心率变异时域分析指标比对照组减低(P<0.01),而原发性高血压合并糖尿病患者PNNSO进一步减低(P<0.05)。结论:原发性高血压患者自主神经功能受损,伴糖尿病患者迷走神经功能进一步受损。

Objective： The purpose of the present study was to investigate the change rule of autonomic nerve in primary hypertension with diabetes.Methods：The heart rate variabihty（HRV） of 24 hours in 37 patients with primary hypertension associated with diabetes were tested,and compared with those in hypertension patients of almost same age. Results：The heart rate of those primary hypertension patients was lower than that of the control group（P〈 0.01）, and the PNNSO of the patients with primary hypertension associated with diabetes was further decreased（P〈 0.05）. Conclusion： The autonomic nerve of the patients with primary hypertension was impaired, and the pneumogastric nerve of those patients with primary hypertension associated with diabetes was further impaired.