摘要
目的观察加替沙星治疗尿路感染的疗效及安全性。方法将80例尿路感染患者随机分成2组:加替沙星组40例,口服,0.4g·d-1;左氧氟沙星治疗组40例,口服,0.4g·d-1。疗程7d或14d。结果加替沙星组和左氧氟沙星组治疗尿路感染的总有效率分别为97.5%和82.5%(P<0.05);细菌清除率分别为96.2%和84.3%(P<0.01);不良反应发生率分别为5%和7.5%。结论加替沙星治疗尿路感染疗效确切,安全性高。
OBJECTIVE To evaluate the clinical efficacy and safety of gatifloxacin. METHODS Eighty patients with urinary infection were randomly and equally divided to receive gatifloxacin （40 cases） or levofloxacin （40 cases） at 0. 4g·d for 7d or 14d in both groups. RESULTS The total effective rate of gatifloxacin group and levofloxacin group was 97.5% and 82.5% respectively （P〈0.05）, the bacterial clearance rate was 96.2% and 84.3% （P〈0.01）,and the incidence of adverse reactions was 5% and 7.5%. respectively. CONCLUSIONS Gatifloxacin is safe and effective for urinary tract infection.
出处
《中南药学》
CAS
2005年第4期250-251,共2页
Central South Pharmacy
关键词
加替沙星
左氧氟沙星
尿路感染
gatifloxacin
levofloxacin
urinary tract infection
