3种不同方法治疗放射性食管炎的临床观察

Clinic Observation of Three Different Treatments for Radiation Esophagitis

目的探讨放射性食管炎的治疗方案。方法回顾性分析69例胸部恶性肿瘤患者(食管癌48例,肺癌21例),放射治疗(66～70Gy)后致放射性食管炎的治疗疗效。结果69例放射性食管炎患者随机分为3组。治疗1组为口服甘露醇+庆大霉素+地塞米松混合液,10ml/次,3次/天,第1～7天;治疗2组为静脉滴注抗生素,1次/天,第1～7天;治疗3组为口服与静滴抗生素,第1～7天。治疗1周后,治疗1组和治疗3组有效率明显高于治疗2组(P<0.05),治疗3组有效率又高于治疗1组(P<0.05)。结论口服甘露醇+庆大霉素+地塞米松联合静脉滴注抗生素是治疗放射性食管炎较为有效的方法。

Objective To explore the treatment of radiation nesophagitis in thoracic tumor.Methods The respouse of three different treatments was observed in 69 patients（48 oesphage cancer and 21 lung cancer） suffering from radiation nesophagitis, Results Those patients were random divided into three groups by retrospectively investigation, Oral mannite mixture as the first group, 10ml one times,3 times one day, from one day to the seventh day.Antibiotics by intravenous drip as the second one, 1 times one day ,3 times one day, from one day to the seventh day.Combined treatment as the third one. The effective percentage of esophagitis in oral mannite mixture group is more increasiing than that in intravenous drip group. Of those, treatment of oral mannite mixture and concurre intravenous drip antibiotics is the best one. Conclusion It is the best effective treatment of raldiation esophagitis by oral mannite mixture and concurrent intravenous drip antibiotics.