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严重创伤患者细胞免疫功能变化和预后相关性研究 被引量:9

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摘要 目的探讨严重创伤患者T淋巴细胞亚群变化特点以及与预后的关系。方法20例严重创伤患者于入院第1天晨抽取肘静脉血2mL,对照组为20例健康体检者,晨空腹抽取肘静脉血2mL,分别检测T淋巴细胞亚群并进行统计学分析。结果观察组CD3+、CD4+亚群均比对照组下降非常显著(P均<0.001),而观察组CD8+亚群、CD4+/CD8+比值较对照组无明显下降(P>0.05)。恶化组与好转组CD3+、CD4+、CD8+及CD4+/CD8+比值均无统计学意义(P均>0.05)。结论严重创伤患者T淋巴细胞亚群发生明显变化,并导致细胞免疫功能下降;而恶化组与好转组间T细胞亚群变化似乎不明显。
出处 《中国急救医学》 CAS CSCD 北大核心 2005年第8期606-607,共2页 Chinese Journal of Critical Care Medicine
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参考文献6

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