摘要
利用电喷雾离子阱质谱(ES-ITMS)技术进行了金鸡纳中4种喹啉类生物碱(奎宁、奎尼定、辛可宁和辛可尼定)的电喷雾质谱研究。在优化的质谱条件下,正离子全扫描时,4种生物碱都易形成带一个质子的分子离子;进一步碰撞诱导解离四种母离子,二级质谱表明羟基丢失、奎宁环断裂及重排为其主要裂解方式。
The MS behaviors and dissociation laws of four alkaloids in Cinchona were studied by direct infusion into electrospray ion trap mass spectrometry (ESI-ITMS). The analytes (dissolved in methanol) easily formed molecular ions ([M+H]^+) in positive detection mode. In CID detection mode, the simple substituents such as -OH were easy to loss in the four alkaloids, and the dissociation and rearrangement of quinuclidine were also the primary behaviors of those analytes.
出处
《分析科学学报》
CAS
CSCD
2005年第4期390-392,共3页
Journal of Analytical Science
基金
湖北省青年杰出人才科学基金(No.2002AC004)