昆明地区人群超重肥胖与血糖、血胰岛素水平及2型糖尿病发病的关系研究

Research for the Relationship between Obesity, blood sugar, insulin and Type 2 Diabetes in Kunming

[目的]探讨昆明地区人群体质指数及不同肥胖类型与血糖、血胰岛素及2型糖尿病发病的关系,以指导开展2型糖尿病预防控制工作。[方法]选取昆明地区新近发现的2型糖尿病患者131例,进行1:1匹配病例对照研究。[结果]与对照相比,超重者和肥胖者患2型糖尿病的危险明显增加,OR值分别为6.489和14.524,且向心性肥胖者更易发生糖尿病;同时,在非糖尿病人群中,随着体重指数的增加,胰岛素分泌量逐渐增加,胰岛素抵抗程度也显著升高。[结论]超重肥胖尤其是向心性肥胖已成为昆明地区人群2型糖尿病的重要危险因素,应积极采取生活方式干预措施进行控制预防2型糖尿病。

Objective To explore the relationship among Body Mass Index （BMI）, blood sugar, insulin, aswell as type 2 diabetes to guide the prevention and control of type 2 diabetes. Methods To choose 131 patients with type 2 diabetes to do the case control study （1：1） Results Comparing to the controls, the overweight and the obesity may increase the risk of happening type 2 diabetes （the number of OR is respective 6.489 and 14.524）. With BMI increasing, the number and the resistance degree of insulin also rose. Condusion Overweight and Obesity has become a major risk factor to type 2 diabetes, and should take measures to prevent and control type 2 diabetes.