经皮腔内冠状动脉成形术后CK-MB及TNT的变化

CHANGES OF SERUM CREATINE KINASE AND TROPONIN T AFTER PERCUTANEOUS CORONARY INTERVENTION

①目的观察冠心病病人经皮腔内冠状动脉介入治疗(PTCI)后心肌肌酸激酶同工酶(CK-MB)及心肌肌钙蛋白T(TNT)值的变化.②方法检测105例冠心病病人PTCI术前、术后6～8 h、16～24 h血液中CK-MB及TNT的含量.③结果CK-MB于术后6～8 h及16～24 h均较术前升高,16～24 h最高,但三者之间无显著性差异(F＝2.26,P＞0.05);TNT值于术后6～8 h及16～24 h均较术前升高,16～24 h最高,与术前及术后6～8 h相比,差异有统计学意义(F＝5.02,q＝4.57、5.79,P＜0.05).④结论TNT在检测心肌受损方面优于CK-MB,CK-MB及TNT的变化与PTCI有关.

Objective To evaluate the changes of creatine kinase and troponin T after percutaneous transluminal coronary intervention（PTCI）. Methods PTCI was done in 105 patients between 1997 and 2004. Blood samples were collected before and 6-8h,16-24h after the procedures for CK-MB and TNT. Results CK-MB was higher after the procedures, but they didn＇t show any statistical difference （F=2.26,P〉0.05）. TNT was also higher after the procedures. In 16-24h group, it had significant difference with that at 6-8h and before the procedures （F=5.02, q=4.57,5.79;P〈0.05）. Conclusion TNT is more sensitive than CK-MB. The changes of CK-MB and TNT are related with PTCI.