无溶剂条件下Yb(OTf)_3催化的亚甲基化合物和醛的Knoevenagel反应

Yb(OTf)_3 Catalyzed Knoevenagel Reaction of Methylene Compounds with Aldehydes under Solvent-free Condition

在Yb(OTf)3催化下,不用任何溶剂,将活泼亚甲基化合物和各类醛进行Knoevenagel反应,得到相应的取代烯烃衍生物.此法操作简便,对环境友好,具有很高的反应产率,且副产物少;此外,催化剂能够在进行反复回收利用之后仍然保持很高的催化活性.

Yb（OTf）3 catalyzed efficiently Knoevenagel condensation of active methylene compounds with various aldehydes under solvent free condition was described as a method for preparation of substituted olefins. The process is operationally simple, environmentally benign and has excellent yield without any side reactions. Furthermore, the catalyst could be recovered conveniently and reused efficiently.