摘要
观察三物白散加味方对肿瘤多药耐药(MDR)基因表达的影响。以三物白散加味方含药血清加入人胃癌SGC-7901细胞中,观察MDR基因表达的变化。结果:三物白散加味方可降低人胃癌SGC-7901细胞MDR基因表达率。提示三物白散加味方临床不易产生多药耐药,并可作为MDR逆转剂使用。
To observe the effect of Modified “Sanwubai Powder”in affecting Multidrug resistance(MDR) gene exptession of tumor.Serum containing Modified“Sanwubai Powder” was added to SGC-7901 cells of human carcinoma of the stomach so as to observe the changes in MDR gene expression.Result:Modified “Sanwubai Powder” could reduce the MDR gene expression rate of SGC-7901 cells of human carcinoma of the stomach. Conclusion: Modified “Sanwubai Powder”is able to reverse the MDR of the SGC-7901 cells of human careinoms of the stomach in clinic.
出处
《上海中医药杂志》
北大核心
2005年第8期59-60,共2页
Shanghai Journal of Traditional Chinese Medicine
基金
江苏省教育厅自然科学基金项目(96KJB360006)