醛与二乙基锌的手性催化不对称加成研究进展

Progress in the Asymmetric Addition of Diethyl Zinc to Aldehydes Using Chiral Catalyst

对最近国内在醛与有机锌的手性催化不对称合成方面使用的新型手性催化剂作了简单的总结,主要有β-氨基醇类、手性氨基酚类、手性磷试剂、手性方酰胺类.并给出了其反应条件及一般结果.

In this review, four kinds of chiral catalysts used in the asymmetric addition of diethyl zinc to aldehydes are presented, the catalysts include β- aminoalcohols, aminophenol, chiral phosphorus reagent and chiral squaric acid amides. Also the conditions used in the reaction and normal results are summarized.