瑞芬太尼与芬太尼用于气管插管及麻醉苏醒期血流动力学与拔管条件的比较

Comparison of Extubating Conditions and Hemodynamic Changes in Intratracheal Intubation and Recovery with Remifentanil or Fentanyl

目的:研究瑞芬太尼与芬太尼对患者气管插管及苏醒期血流动力学变化与拔管条件的比较。方法:40例择期颅脑手术的患者麻醉诱导和麻醉维持分别用瑞芬太尼(R组)或芬太尼(F组)。观察气管插管及苏醒期血流动力学变化与拔管条件等情况。结果:麻醉诱导后气管插管1～5min内血流动力学变化幅度R组明显小于F组(P<0.05);术后苏醒恢复状况及拔管条件R组优于F组(P<0.05)。结论:瑞芬太尼在气管插管和麻醉苏醒期的血流动力学更稳定,拔管条件优,并发症少。

Objective：To study and compare of extubating conditions and hemodynamic changes in intratracheal intubation and recovery with remifentanil or fentanyl. Methods ： Forty patients undergoing neurosurgery were induced and maintained with remifentanil （R group） or fentanyl （F group）. Extubating conditions and hemodynamic changes in intratracheal intubation and recovery profil of anesthesia were observed. Results ：Hemodynamic changes during intubation were significantly fewer in R group than in F group （P〈0. 05）. Recovery from anesthesia and extubating conditions were better in R group than in F group. Conclusion：Remifentanil anesthesia can offer superior intraoperative hemodynamic stability in tracheal intubation and recovery from anesthesia and extubating conditions are better compared with fentanyl.