APACHEⅡ评分在急性有机磷中毒预后判断中的作用研究

Research the Prognosis of Acute Organophosphate Insecticide Poisoning with Acute Physiology and Chronic Health EvaluationⅡ

目的:应用急性生理学及慢性健康状况评分(APACHEⅡ)评价有机磷农药中毒患者的病情危重程度并判断其预后,证明其应用的有效性。方法:连续观察入EICU有机磷农药中毒资料完整患者41例,分别计算各自APACHEⅡ评分,并进行验证;建立回归模型。结果:41例患者的APACHEⅡ评分为0～34分,平均(9.78±8.96)分。31例存活者评分(5.48±4.43)分,10例死亡者评分(23.1±5.55)分,两者差异显著(P<0.01)。进行logistic回归分析后得到死亡风险模型。结论:APACHEⅡ评分系统可应用于有机磷农药中毒患者危重程度及预后的评估;APACHEⅡ评分可为合理利用资源及开展学术交流提供参考。

Objective： Use acute physiology and chronic health evaluationⅡ（APACHEⅡ） to assess the severity of the illness and prognosis of the organophosphate insecticide poisoning patients. Methods： 41 organophosphate insecticide poisoning patients who were admitted to EICU were observed, then APACHE Ⅱ score was calculated, the prognostic value of this system was assessed, finally relationship analysis was done between mortality and APACHE Ⅱ , regression model was established. Results：APACHE Ⅱ scores of these patients were in the range of 0 to 34, average （9.78±8.96）, with average score of （ 5.48±4.43 ）for 31 survivors and （23.1±5.55） for nonsurvivors. The difference between these two groups of patients was significant （ P 〈0.01）. There was a significant correlation between APACHE Ⅱ score and mortality, regression model was established. Conclusions： APACHE Ⅱ score system can be used to predict the prognosis of organophosphate insecticide poisoning patients; On the basis of APACHE Ⅱ score system organophosphate insecticide poisoning resource can be used rationally and academic intercourse can proceed effectively.