脑梗死患者血清C-反应蛋白水平与病情及预后的关系

Relation between serum C-reactive pro tein(CRP)levels and severity and prognosis after cerebral infarction

目的研究脑梗死患者血清C-反应蛋白(CRP)水平与病情的严重性及预后的量化关系。方法对病程在2周以内的90例脑梗死患者在入院时进行血清CRP水平的测定,应用美国国立卫生研究院卒中量表及Barthel指数记分对入选患者在入院时及3个月后的神经功能缺损程度进行评分。结果血清CRP水平与当时及病后3个月神经功能缺损的严重程度显著相关(P<0·01),且这种相关性存在着量化的关系。结论根据脑梗死患者病后2周内的CRP水平可以对病情的严重性及预后进行量化的判定。

Objective To study relation between C-reactive protein （CRP） and severity and prognosis after ischemic stroke. Methods Ninety patients with ischemic stroke （the course of disease less than 2 weeks） were examined with National Institutes of Health Stroke Scale （NIHSS） and Barthel Index （BI） score on admission and 3 months after admission. CRP was measured on admission. Results The levels of serum CRP was significantly and quantitatively correlated with severity and prognosis after ischemic stroke （ P 〈 0.01 ）. Conclusion Serum CRP within 2 weeks after onset was associated with severity and could predict prognosis after ischemie stroke.