摘要
目的:考察苯妥英钠中毒浓度与下肢运动障碍间的相关性。方法:收集苯妥英钠血清浓度监测结果,并与下肢运动障碍间关系进行统计学分析。结果:苯妥英钠血清浓度≥30mg·L-1时,下肢运动障碍与苯妥英钠中毒浓度相关,有显著性意义(Fisher确切概率法检验,P=0.000)。结论:30mg·L-1为下肢运动障碍阈值,苯妥英钠中毒浓度≥30mg·L-1可致下肢运动障碍,为临床诊断苯妥英钠中毒提供了新的依据。
Objective: To study the correlation between phenytoin poisoning and the impediment to leg activity. Method : The results of phenytoin in serum were collected and statistically compared with the impediment to leg activity, Result: When the concentration of pbenytoin in serum was more than 30 mg·L^-1 , the correlation between them was significant (F-test, P=0. 000). Conclusion: Phenytoin poisoning may result in an impediment to leg activity, which provides a new evidence for the clinical diagnosis of phenytoin poisoning,
出处
《药物流行病学杂志》
CAS
2005年第2期79-80,共2页
Chinese Journal of Pharmacoepidemiology
关键词
苯妥英钠
中毒
下肢
运动障碍
Phenytoin
Poisoning
Lower limb
Impediment to activity