雾化吸入沙丁胺醇治疗小儿哮喘急性发作

Effects of Inhalation of Salbutamol in the Treatment of Children with Asthma Acute Episode

目的:观察沙丁胺醇吸入治疗对儿童哮喘急性发作期的临床疗效。方法:将近3年临床诊断为哮喘的住院患儿81例,分为治疗组46例,对照组35例,对平喘效果进行对比观察。两组的基础治疗相同,治疗组在基础治疗的同时采用沙丁胺醇,每次0.03ml·kg-1,加入0.9%氯化钠注射液至2ml,放入百瑞驱动式喷雾器吸入,在开始时每隔20min吸入1次,连续吸入3次,每次吸入时间5-8min,以后每隔4-6h重复吸入1次,疗程3d。对照组则用氨茶碱,每次5mg·kg-1,ivd,q6h,疗程3d。结果:治疗3d后,治疗组哮喘完全缓解42例(91.3%),部分缓解4例(8.7%),对照组哮喘完全缓解26例(74.3%),部分缓解9例(25.7%)。结论:治疗组哮喘完全缓解率明显高于对照组(P<0.05)。

Objective： To evaluate the clinical effect of inhalation of salbutamol sulfate on children asthma acute episode. Method： 81 cases of children with asthma were divided into two groups： observation group （46 cases） and control group （35 cases）. With the same basic treatment, the observation group inhaled salbutamol sulfate of 0.03 ml/kg/20 min, three times, 5-8 min/time, and then one time/4-6 h, The total period was three days. Result： After 3 days, 42 （91.3% ） cases of the observation group were completely relieved, and 4 （8.7%） cases, partly relieved. 26 eases （74.3% ） of the control group got completely relieved and 9 （25.7%） cases, partly relieved. Conclusion： The complete relief rate of the observation group is higher than that of the control group.