摘要
目的初步探讨无症状性脑梗死(ACI)患者认知功能损伤与脑梗死灶间的关系。方法采用视觉保持测验(VRT)对112例ACI患者的认知功能损伤进行评测,并分析脑梗死灶数量、体积、位置等不同因素对VRT得分的影响。结果ACI组VRT的正确得分明显低于对照组(14.5±3.2vs22.8±3.3,P<0.05),错误得分明显高于对照组(18.1±5.1vs7.6±3.6,P<0.05);且ACI组VRT的正确得分随梗死灶数量的增加而逐渐降低(F=15.872,P<0.05),与梗死灶的总体积呈负相关(r=-0.5984,P<0.05),而VRT错误分与梗死灶的总体积呈正相关(r=0.4689,P<0.05)。结论经VRT测试后发现,ACI患者存在明显的视觉空间记忆损伤,这种认知功能损伤可能与脑组织受损有一定关系。
Objective To observe the relationship between visual-spatial perception impairment and the characteristics of asymptomatic cerebral infarction ( ACI). Methods After evaluating the cognitive impairment of 112 patients with ACI using the Revised Visual Retention Test (VRT), we compared the result of VRT test among different groups grouped by number, size and location of the cerebral infarction. Results The total score of the patients with ACI with correct answers in VRT was significantly lower than that of the controls ( 14.5±3.2 vs 22.8±3.3, P 〈0.05) , while total score of the patients with wrong answers was higher than that of the controls( 18.1 ±5. 1 vs 7.6 ±3.6, P 〈 0.05 ), The correct answer score of the patients in VRT reduced gradually with the increase of number of cerebral infarction ( F = 15. 872, P 〈 0.05 ) , and negatively correlated with the size of cerebral infarction (r = - 0. 5984, P 〈 0, 05). The wrong answer score of the patients in VRT was positively correlated with the size of cerebral infarction ( r = 0. 4689, P 〈 0.05 ). Conclusion There existed significant visual-spatial perception impairment in ACI patients, which attributed partially to lesion of cerebral tissue.
出处
《中华物理医学与康复杂志》
CAS
CSCD
北大核心
2005年第8期488-491,共4页
Chinese Journal of Physical Medicine and Rehabilitation