小剂量红霉素治疗早产儿动力性胃肠功能紊乱的效果观察及护理

The effect of taking low-dose erythromycin on dynamic gastrointestinal dysfunction of premature infants and its nursing

目的探讨小剂量红霉素治疗早产儿胃肠功能紊乱的疗效及应用时的护理方法。方法将46例动力性胃肠功能紊乱早产儿按时间先后分为两组,对照组20例,治疗组26例。两组均给予早期合理喂养、对症处理、胃肠外营养等处理,治疗组在常规治疗的基础上加用小剂量红霉素[3～5mg/(kg·d)]进行干预。结果治疗组在开奶时间、生理性体质量下降恢复时间、出院时间方面明显短于对照组(P<0.01),治疗组疗效明显高于对照组(P<0.01),且无明显不良反应发生。结论小剂量红霉素可以显著改善早产儿胃肠动力不足,使早产儿及早行胃肠内营养,促进体质量增长。

Objective To observe the effect of taking low-dose erythromycin on dynamic gastrointestinal dysfunction of premature infants and its nursing. Methods Forty-six premature infants with dynamic gastrointestinal dysfunction were divided into two groups according to the sequences of their birth date, 20 infants for control group, the others for experimental group. Both groups were provided with reasonable feeding, the illness handle and the nutrition in venous channel, while the experimental group take low-dose erythromycin [3-5 mg/（kg·d）] to intervene. Results The experimental group＇s time of breast feeding, recovery from weight reduction,leaving hospital was shorter than the control group＇s （P〈0.01）, treatment effect of experimental group was higher than that of control group （P〈0.01） with no obvious adverse effect. Conclusion Low-dose erythromycin can improve gastrointestinal dynamic of premature infants and ingestion of nutrition, which can also cause the increase of weight.