我院感染常见细菌分布及其对抗菌药物耐药性分析

Analysis of Bacterial Distribution and Resistance of the Common Infections in Our Hospital

目的:了解医院感染致病菌分布的临床特点及其耐药性情况。方法:对2003年11月～2004年11月临床标本中分离的细菌进行鉴定及药物敏感试验,并作统计分析。结果:分离细胞中排在前列的为肺炎克雷伯菌、大肠埃希菌、金黄色葡萄球菌,其中大肠埃希菌、肺炎克雷伯菌主要来源于痰、尿;革兰氏阴性菌对头孢噻肟、头孢曲松等耐药率较高,革兰氏阳性菌对克拉霉素、红霉素等耐药率较高;白色念珠菌对酮康唑、咪康唑的耐药率均超过了50%。结论:了解医院感染常见致病菌的分布和耐药趋势,进行耐药性监测,对指导临床合理应用抗菌药物是必要的。

Objective： To know the features of bacterial clinical distribution and drug resistance, Methods： To analyze the data of pathogen identification and susceptive test of bacteria isolated from samples during 2003. 11 to 2004, 11. Results： Bacteria ranking the front places were Klebsiella peneumoniae other, escherichia coli, staphylococcus, escherichia coli and Klcbsiella peneumoniae derived from sputum or urine. The resistance rates of Gram- negative bacilli to cefotaxime and cefatriaxone were higher, the resistance rates of Gram- positive bacteria to clarithromycin and erythroycin were higher. The resistance rates of Candida albicans to ketoconazol and miconazole were over 50%. Conclusion： To investigate the tendency of bacterial distribution and monitor its drug-resistance are important to guide the application of antibiotic drugs in hospital.