彩色多普勒超声对周围型肺癌组织学类型诊断价值的探讨

The diagnostic value of Doppler ultrasound on peripheral lung cancer

目的:探讨多普勒超声对周围型肺癌病理定性及组织学类型的诊断价值.方法:对59例周围型肺癌的多普勒超声与免疫组织化学方法进行对照分析.结果:免疫组化图片显示,腺癌的微血管及较大血管密度均明显高于鳞癌,较大的血管比例约3.74:1.能量多普勒血流图(CDE)显示,73.7%(28/38)的腺癌血流信号丰富,血供分级达Ⅱ～Ⅲ级;而76.2%(16/21)的鳞癌血流信号稀少,甚至于探测不到.脉冲多普勒(PD)显示,腺癌的血流频谱为相对低阻型,阻力指数(RI)约0.51±0.04,而鳞癌的波峰高尖,RI约0.76±0.03,二者RI组间相比,t=2.197,P<0.05,差别有显著性意义.结论:多普勒超声在鉴别周围型肺腺癌和鳞癌方面有一定的应用价值.

Objective： To evaluate Doppler ultrasound on peripheral lung cancer. Methods： Comparison was made between Doppler image and pathological immunochemistry study in 59 cases of peripheral lung cancer. Results： The distribution of micro-or larger vessels in adenocarcinoma was denser than that in squamous cell carcinoma with a ratio of about 3.74 ： 1 in immunochemistry study. The blood flow signal was thick in 73.7%（28/38） in adenocarcinoma with blood supply grade Ⅱ-Ⅲ while thin blood single was observed in 76.2%（16/21） of the squamous cell carcinoma on the power Doppler imaging （PDI）. Pulse Doppler （PD）： lower resistant spectrum was observed in adenocarcinoma with resistance index （ RI）0.51±0.04versus 0.76 ± 0.03 in squamous cancer and consequently significant difference found between them （ t = 2.197, P 〈 0.05）. Conclusion：There is certain practical value of Doppler imaging in certifiing adenoor squamous cancer for peripheral pulmonary lesions.