乳腺肿块MSCT灌注研究

Clinical Evaluation of MSCT Perfusion for Breast Mass

目的:评价MSCT灌注测量对乳腺肿块病变的诊断价值。方法:对81例体检或钼靶检查发现乳腺肿块性病变者(84个)行多层螺旋CT灌注扫描,由去卷积算法得出肿块血流动力学参数(BF、MTT、BV),并按病理结果的良、恶性分组,行t检验。结果:恶性病变组:血流量为(0.74±0.44)ml/(min·ml),平均通过时间(22.77±7.65)s,血容量0.23±0.08;良性病变组:血流量为(0.47±0.53)ml/(min·ml),平均通过时间(26.71±12.93)s,血容量0.18±0.12。血流量、血容量在乳腺良、恶性肿块之间的差异有统计学意义(P值分别为0.017、0.015)。结论:乳腺恶性肿块的血流量和血容量明显高于良性肿块,在乳腺肿块性病变的良恶性鉴别诊断中有较高的参考价值。

Objective： To evaluate the diagnostic value of MSCT perfusion for breast mass. Method： 81 cases with breast mass found by health examination or mammography were scanned by MSCT perfusion, then hemodynamic parameters （BF, MTT,BV） were calculated by deconvolution arithmetic. According to the pathologic results, the cases were classified into benign and malignant groups.t test was used for stastistics as well （size of test α=0.05）. Results：In the malignant group,the BF was （0.74±0.44）ml/（min·ml）,MTT was （22.77±7.65）s,and BV was 0.23±0.08. While in the benign group,the BF was （0.45±0.53）ml/（min · ml） ,MTT was （26.71±12.93）s,and BV was 0. 18±0.12. As for BF and BV,there were significant difference between the two groups of malignancy and benign （P value are 0. 017 and 0. 015 respectively）. Conclusion：The BV and BF of malignant mass are higher than benign mass. This character can be used to differentiate the nature of breast lesions to a certain extem.