老年冠心病患者血清胆红素与血脂含量测定

Level of serum total bilirubin and lipids in delderly patients with coronary heart disease

目的:研究老年冠心病患者血清胆红素与血清脂质水平的意义。方法:测定97例老年冠心病患者及48例正常老年对照组的血清总胆红素(TB)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白-胆固醇(HDL-C)、低密度脂蛋白-胆固醇(LDL-C)、载脂蛋白Al(Apo Al)、载脂蛋白B(ApoB_(100) )、脂蛋白(a)[Lp(a)]水平并分析之。结果:老年冠心病患者血清TB 含量显著低于同龄正常对照组(P<0. 05) ;老年冠心病患者血清TG、LDL-C 水平显著高于对照组(P<0. 05) ;而HDL-C 水平却极显著低于对照组(P<0. 01) ;血清TC、ApoA I、ApoB 及Lp(a) 水平两组比较无显著性差异。结论:老年人低血清胆红素可能是动脉粥样硬化和冠心病危险因素之一。

Objective： To explore the variation of concentration of serum total bilirubin （TB） and lipids in patients with coronary heart disease （CHD）. Metbods： A total of 155 persons were divided into CHD group （n=97） and normal group （n=48）. The levels of bilirubin and lipids in serum were measured and compared. Results： The concentration of serum TB in CHD group was significant lower than that in normal group （P〈0. 05） . The serum triglyeeride, low density lipoprotein cholesterol levels in CHD group were obvious higher than those in the normal group （P〈0.05） ;high-density lipoprotein-cholesterol obviously decreased in CHD group （P〈0.01）; There was no significance difference of total cholesterol and apolipoprotein （Apo） A1, ApoB100, lipoprotein （a） [Lp （a）] between two groups （P〉0.05）. Conclusion： The low concentration of serum TB may be a risk factor for aged CHD patients.