5Thernton AM,Shevach EM.CD4+CD25+immunoregulatory Tcells suppress polyclonal T cell activation in vitro by inhibiting in-terleukin 2 production[J].J Exp Med,1998,20,188(2):287-296.
6Ithoh M,Takahashi T,Sakaguchi N,et al.Thymus and autoim-munity prnduction of CD4+CD25+naturally anergic and sup-pressive T cells as a key function of the thyus in maintaining im-munologicself-tolerance[J].J Immunol,1999,162(9):5317-5326.
7Wolf AM,Wolf D,Steurer M,et al.Increase of regulatory T cellsin the peripheral blood of cancer patients[J].Clin Cancer Res,2003,9(2):606-612.
8Ormandy LA,Hillemann T,Wedemeyer H,et al.Increased popu-lations of regulatory T cells in peripheral blood of patients withhepatocelluar carcinoma[J].Cancer Res,2005,65(6):2457-2464.
