170例乳腺癌术后全身骨显像病例分析

Clinical analysis of post-operation whole-body bone imaging of 170 patients with breast cancer

目的探讨核素全身骨显像对乳腺癌术后骨转移的诊断价值.方法对170例乳腺癌术后患者静脉注射99mTc-亚锡亚甲基二膦酸盐(MDP)740MBq,3h后行SPECT全身骨显像.结果 66例乳腺癌患者发现骨转移,阳性率38.82%.骨转移与患者年龄无明显相关;乳腺癌术后2～5年是骨转移高峰期.全身多发骨转移病灶37例,明显高于单发病灶29例.结论核素全身骨显像可作为诊断乳腺癌术后骨转移的常规方法,患者应定期进行骨显像检查.

Objective To investigate the diagnosis significance of radionuclide imaging in whole-body bone on bone metastases of breast cancer post-operation. Methods Whole body bone imaging of 170 patients with breast cancer in the postoperation was carried on by SPECT after 3h of ^99mTc-MDP 740MBq injections in vein. Results The results showed that 66 bone metastases were found in patients with breast cancer. The incidence of bone metastases reached 38. 82 %. There is not obvious relation between bone metastases and patient＇s age. The peak of bone metastases is from 2 to 5 years after breast cancer operation. 37 cases are multi focus in present investigation, and 29 cases are single focus. Multi focus is obvious higher than single focus. Conclusion ^99m Tc-MDP SPECT whole-body bone scan can be used as an ordinary diagnostic method of bone metastases in breast cancer post-operation, and the patients should he periodically checked up by ^99mTc-MDP SPECT whole-body bone scan.