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核素骨显像在肺癌骨转移诊断中的应用 被引量:9

The clinical application of radionuclide bone imaging in patients with lung cancer
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摘要 目的分析肺癌骨转移特点,评估放射性核素骨显像诊断肺癌骨转移的价值.方法对570例肺癌患者静脉注射99mTc-MDP,3~4h后行全身静态骨显像.结果 570例肺癌患者中381例骨显像阳性,占66.8%;其中12例(3.1%)经随访及X线、MRI多次检查证实为假阳性.多发病灶者272例,占骨转移的74.3%;骨转移病灶分布,肋骨293例,脊椎骨280例,盆骨86例,其他胸骨、肩胛骨、颅骨、四肢骨等.不同病理类型分析,腺癌阳性率最高(70.2%),鳞癌最低(51.6%).结论肺癌骨转移以多发性病灶为主,骨转移部位以肋骨、脊椎骨多见;腺癌易发生骨转移.对单个肋骨阳性患者应密切随访,定期复查.骨显像对肺癌临床分期、治疗方案选择及预后评估均有重要的临床价值. Objective To investigate the clinical value of bone scintigraphy in patients with lung cancer. Methods Five hundreds and seventy patients were examined by bone scintigraphy. The whole-body scan was performed at 3h to 4h after injection of ^99mTc-MDP in vein. Results Among 570 cases, 381 cases were found positive and 12 in it were false positive conformed by follow-up. Multiple bone lesions in 272(74.3 % ) . The common metastatic bone lesions were in ribs, vertebras, and pelvis. Conclusion Multiple bone metastases is one of the characters of lung cancer. Bone scintigraphy plays an important role in clinical staging, therapy scheme selecting, and predicting of prognosis.
出处 《重庆医学》 CAS CSCD 2005年第8期1136-1136,1138,共2页 Chongqing medicine
关键词 核素骨显像 肺癌 骨转移 radionuclide bone imaging lung caneer bone metastases
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参考文献4

  • 1马寄晓 刘秀杰.使用临床核医学[M].原子能出版社,2002.327.
  • 2Erturan S, Yaman M, Aydin G,et al. The role of wholebody bone scanning clinical factors in detecting bone metastases in patients with non-small cell lung cancer[J].Chest, 2005,127(2) :449.
  • 3Cheran SK, Herndon JE, Patz EF jr. Comparison of whole-body FDG-PET to bone scan for detection of bone metastases in patients with a new diagnosis of lung cancer[J]. Lung Cancer, 2004,44 (3): 317.
  • 4Mena E, Camacho V, Estorch M, et al. 99mTc-depreotide scintigraphy of bone lesions in patients with lung cancer [J]. Eur J Nucl Med Mol Imaging,2004,31(10):1399.

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