母牛分支杆菌菌苗治疗糖尿病合并初治肺结核的临床分析

The clinic analysis on the effect of Mycobacterium vaccae vaccine to treatment outcome of new diabetes complicated pulmonary tuberculosis caces

目的探讨母牛分支杆菌菌苗(简称微卡)治疗糖尿病合并肺结核的疗效。方法同期选取40例糖尿病合并肺结核初治患者,随机分为A、B组。A组以常规抗痨治疗(2HRZE/4HR),B组在常规抗痨治疗的基础上加用微卡治疗2月。结果B组结核病灶消散吸收、空洞完全或部分闭合、痰结核菌阴转速度均明显快于A组(P<0.05),且不良反应少见。结论微卡可用作糖尿病合并肺结核的免疫治疗。

Objective To evaluate the effect of Mycobacterium vaccae vaccine （M. vaccae vaccine） to treat- ment outcome of new diabetes complicated with pulmonary tuberculosis cases. Methods 40 cases were divided into A group （20 cases） and B group （20 cases）. The cases in two groups were treated by the same chemotherapy regi- men of 2HRZE/4HR,the group B were treated immunotherapy with M. vaccae vaccine for 2 months. Results Compared with group A,the effects on improving of X-ray manifestation and sputum smear-negative conversion rates in group B were better （P〈0. 05）. The side effect of M. vaccae vaccine were rare. Conclusion The M. vaccae vaccine was helpful for new diabetes complicated with pulmonary tuberculosis.