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姑息医学中的循证医学证据 被引量:5

Clinical Evidence for Palliative Medicine
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摘要 为了解姑息医学中的循证医学证据,我们检索了Cochrane图书馆(2005年第3期),对针对疾病终末期常见症状的系统评价证据进行了总结。结果发现,阿片类药物可以改善终末期病人的呼吸困难;口服吗啡和氢吗啡酮对癌痛有效;体内外放疗及二膦酸盐对肿瘤转移性骨痛有效;姑息性化疗能提高晚期或已发生转移的结肠癌病人的生存质量。 Objective We searched the Cochrane Library( Issue 3, 2005 ) to identity evidence related to palliative treatment. We found that Opioids are effective for the palliation of breathlessness in terminal illness. Oral Morphine and hydromorphone is effective for cancer pain. Radiotherapy and Bisphosphonates can relief pain secondary to bone metastases. Corticosteroids can resolve malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer.
出处 《中国循证医学杂志》 CSCD 2005年第8期648-651,共4页 Chinese Journal of Evidence-based Medicine
关键词 呼吸困难 姑息医学 循证医学 生存质量 Palliative medicine Evidence-based medicine Quality of life
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参考文献12

  • 1Jennings AL, Davies AN, Higgins JPT, Broadley K. Opioids for the palliation of breathlessness in terminal illness [ M/CD]. The Cochrane Database of Systematic Reviews 2001, Issue 4. Oxford: Update Software.
  • 2Wiffen PJ, Edwards JE, Barden J, McQuay HJM. Oral morphine for cancer pain [ M/CD ]. The Cochrane Database of Systematic Reviews 2003, Issue 4. Oxford: Update Software.
  • 3Quigley C. Hydromorphone for acute and chronic pain [ M/CD].The Cochrane Database of Systematic Reviews 2002, Issue 1. Oxford:Update Software.
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  • 7Wong R, Wiffen pJ. Bisphosphonates for the relief of pain secondary to bone metastases [ M/CD ]. The Cochrane Database of Systematic Reviews 2002, Issue 2. Oxford: Update Software.
  • 8Martinez MJ, Roque M, Alonso-Coeno P, Catala E, Garcia JL,Ferrandiz M. Calcitonin for metastatic bone pain [ M/CD]. The Cochrane Database of Systematic Reviews 2003, Issue 3. Oxford: Update Software.
  • 9Macbeth F, Toy E, Coles B, Melville A, Eastwood A. Palliative radiotherapy regimens for non-small cell lung cancer [ M/CD ]. The Cochrane Database of Systematic Reviews 2001 , Issue 4. Oxford: Update Software.
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