摘要
中枢神经系统中存在着内源性镇痛系统的证据,先来自对脑刺激镇痛、阿片镇痛的研究,后来自对针刺镇痛、应激镇痛的研究。因此获知,伤害性信息不是为神经系统被动感受,而是在它向上传递时,受到了内源性镇痛系统的滤过和整合。其中包括脊髓背角和三叉神经脊束核痛敏神经元受到来自脑于下行纤维的抑制。近年来的研究表明,中枢神经系统中存在着的内源性镇痛系统有其复杂性和多样性,至少可将它们分为两大类,一为内源性阿片镇痛系统,另一为内源性非阿片镇痛系统。这在脑刺激镇痛、针刺镇痛和应激镇痛均获证实。
A lot of researches indicate that central nervous system not only exist endogenous opiate analgesic system but also possess endogenous nonopiate analgesic system.The opiate and nonopiate analgesic systems can be selectively activated by defferent environmental or artificial manipulations and modulated the stimulation produced analgesia,acupuncture analgesia and stress-induced analgesia,including the foot shock-induced analgesia,tailshock-produeced analgensia,earshock-induced analgesia,analgesia of cold water swim,analgesia of
immobilization or of restraint and analgesia of a-Deoxy-D-glucose and so on.The existance and description of these modulatory mechanisms have it's multiplicity and important clinical implications for the treatment of pain.
出处
《针刺研究》
CAS
CSCD
1989年第3期306-314,共9页
Acupuncture Research
