拟出国人员乙型肝炎血清标志物检测结果分析

The Analysis on Test Results of Serological Markers of HBV of the Persons Planning to Go Abroad

〔目的〕探讨拟出国人群中乙型肝炎病毒(HBV)的感染情况和乙型肝炎5项血清标志物的模式特征。〔方法〕用酶联免疫吸附试验(ELISA)测定拟出国人员血清中乙型肝炎病毒表面抗原(HBsAg)及其抗体(HBsAb)、e抗原(HBeAg)及其抗体(HBeAb)以及核心抗体(HBcAb)5项HBV血清标志物(HBVM)。〔结果〕3310份血清样本中1946份为全阴性,占检测总数58.79%;1364份为HBVM5项中有1项或1项以上阳性,总阳性率为41.21%。模式共有14种,分为感染期模式组和恢复期模式组,感染期模式组以“1、3、5”和“1、4、5”模式为主;恢复期模式组以“2、5”和“2”模式为主。〔结论〕在拟出国的健康人群中,乙型肝炎的总感染率较高,应加强乙型肝炎病毒的检测,提倡接种乙型肝炎疫苗。

ObjectiveTo study the hepatitis B virus infection status and the different patterns of five serological markers in persons who will go abroad. Methods:HBsAg, HBsAb, HBeAg, HBeAb, HBcAb were tested people who will go abroad by enzyme-linked immunosorbent assay. Results1KG*8946 cases were negative, accounting for 58.79% of the total, in while 1KG*8364 cases were postire, accounting for 41.21% There were 14 different patterns in all, which could be divided into infection pattern group and recovery pattern group. The '135'and '145' were primary pattern in the infection group and'25' and'2' were primary in the recovery group. ConclusionsThe total rate of HBV infection is still high among people to go abroad;were postire HBV testing and prevention should be strengthened.