期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

TLR9的特性及其介导CpG DNA的信号通路 被引量：1

下载PDF
导出
作者 李岩 邢飞跃
机构地区 四川大学华西医学中心感染免疫研究室 暨南大学教育部组织移植与免疫重点实验室
出处 《广东医学》 CAS CSCD 北大核心 2005年第9期1289-1290,共2页 Guangdong Medical Journal
基金 国家自然科学基金资助项目(编号:30471635) 广东省自然科学基金资助项目(编号:04010451)
关键词 TLR9 CPG DNA 信号通路 免疫应答 特异性配体 糖脂结构
分类号 R392 [医药卫生—免疫学]
  • 相关文献

参考文献12

  • 1Medzhitov R, Preston - Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature, 1997, 388(6640) :394.
  • 2Tobias PS, Tapping RI, Gegner JA. Endotoxin interactions with lipopolysaccharide- responsive cells. Clin Infect Dis, 1999, 28(3):476.
  • 3Hemmi H, Kaisho T, Takeuchi O, et al. Small anti- viral compounds activate immune cells via the LTR7 MyD88 - dependent signaling pathway. Nat Immunol, 2002, 3(2):196.
  • 4Hemmi H, Takeuchi O, Kawai T, et al. A Toll - like receptor recognizes bacterial DNA. Nature, 2000, 408(6813):740.
  • 5Chuang TH, Lee J, Kline L, et al. Toll - like receptor 9 mediates CpGDNA signaling. J Leukoc Biol, 2002, 71(3):538.
  • 6Ahmad-Nejad P, Hacker H, Rutz M, etal. Bacterial CpG-DNA and lipopolysaccharides activate Toll - like receptors at distinct cellular compartments. Eur J Immunol, 2002, 32(7): 1958.
  • 7Takeshita F, Gursel I, Ishii KJ, et al. Signal transduction pathways mediated by the interaction of CpG DNA with Toll - like receptor 9. Semin Immunol, 2004, 16(1):17.
  • 8Kerkmann M, Rothenfusser S, Homung V, et al. Activation with CpGA and CpG- B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J Immunol,2003, 170(9) :4465.
  • 9Takauji R, Iho S, Takatsuka H, et al. CpG- DNA- induced IFN- alpha production involves p38 MAPK - dependent STAT1 phosphorylation in human plasmacytoid dendritic cell precursors. J Leukoc Biol, 2002, 72(5): 1011.
  • 10Underhill DM. Toll - like receptors: networking for success. Eur J Immunol, 2003, 33(7): 1767.

同被引文献24

  • 1Chon S Y,Hassanain H H,Pine R,et al.Involvement of two regulatory elements in interferon-γ-regulated expression of human indoleamine 2,3-dioxygenase gene[J].J Interferon Cytokine Res,1995,15(6):517-526.
  • 2Robinson C M,Shirey K A,Carlin J M.Synergistic transcriptional activation of Indoleamine Dioxygenase by IFN-γ and tumor necrosis factor-α[J].J Interferon Cytokine Res,2003,23(8):413-421.
  • 3Tsukahara T,Kimb S,Taylor M W.A search framework for the identification of interferon-responsive elements in DNA sequences-a case study with ISRE and GAS[J].Comput Biol Chem,2006,30(2):134-147.
  • 4Chon S Y,Hassanain H H,Gupta S L.Cooperative involvement of interferon regulatory factor 1 and p91 (Stat1) response elements in interferon-γ-inducible expression of human indoleamine 2,3-dioxygenase gene[J].J Biol Chem,1996,271(29):17247-17252.
  • 5Cory M,Robinson,Phillip T,et al.The role of IFN-γ and TNF-α-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase[J].Interferon Cytokine Res,2005,25(1):20-30.
  • 6Baban B,Hansen A M,Chandler P R,et al.A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation[J].Int Immunol,2005,17(7):909-919.
  • 7Tnani M,Bernard A,et al.Evidence for IRF-1-dependent gene expression deficiency in interferon unresponsive HepG2 cells[J].Biochim Biophys Acta,1999,1451(1):59-72.
  • 8Recht M,Borden E C,Knight E Jr.A human 15-kDa IFN-induced protein induces the secretion of IFN-gamma[J].J Immunol,1991,147(8):2617-2623.
  • 9Mellor A L,Baban B,Chandler P R,et al.Cutting edge:CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling[J].J Immunol,2005,175(9):5601-5605.
  • 10Mellor A,Munn D H.IDO expression by dendritic cells:tolerance and tryptophan catabolism[J].Nat Rev Immunol,2004,4(10):762-774.

引证文献1

二级引证文献3

广东医学
2005年 第9期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部