化学栓塞治疗原发性肝癌合并门静脉瘤栓18例报告

Report of chemoembolization for 18 patients with hepatocellular carcinoma combined with portal vein thrombosis

目的探讨原发肝癌合并门静脉瘤栓的化学栓塞治疗。方法将18例合并门静脉主干或左右大分支瘤栓的原发性肝癌采用肝段或亚肝段动脉化疗加碘油和明胶海绵栓塞。结果全组6、12、18和24个月生存率分别为72.2%(13/18)、44.4%(8/18)、22.2%(4/18)和11.1%(2/18),门脉瘤栓消失率为44.4%(8/18)。结论经肝动脉化疗加栓塞法是治疗合并门脉瘤栓原发性肝癌的的效方法,且栓塞法优于单纯灌注化疗法,特别是肝段或亚肝段动脉化学栓塞法疗效更好。

Objective To study the clinical effectiveness of arterial chemoembolization for hepatocellular carcinoma with portal vein thrombosis. Methods 18 cases of hepateceUular carcinoma combined with portal vein thrombosis were treated with segmental or subsegmental arterial chemoembolization. Results The 6-,12-18-and 24-month survival rate were 72.2%（13/18）,44.4%（8/18）,22.2%（4/18） and 11.1%（2/18）,respectively. The disappearance rate of portal vein thrombosis was 44.4% （8/18）. Conclusion Transcathetet hepatic artery chemoembolization is the effective treatment for hepatoceUular carcinoma with portal vein thrombosis. It is more effective than the simple chemotherapy, especially with segmental or subsegmental arterial chemoembolization.