不同种类和强度的噪声对耳蜗血流的影响

EFFECTS OF VARIOUS NOISES AT DIFFERENT INTENSITIES ON COCHLEAR BLOOD FLOW

本文利用激光多谱勒血流计测量了不同种类和强度的噪声对豚鼠耳蜗血流的影响。结果发现，暴露于１２０ｄＢ，１．５ｋＨｚ纯音中３０ｍｉｎ后，耳蜗血流明显下降，而强度为ｌｌ０ｄＢ时，耳蜗血流没有改变。暴露于１２０ｄＢ、１１０ｄＢ中心频率１．５ｋＨｚ的窄带噪声中３０ｍｉｎ后耳蜗血流明显下降，而强度为１００ｄＢ的同样噪声暴露没有引起耳蜗血流的变化。声暴露停止后，耳蜗血流逐渐恢复，但在３０ｍｉｎ内尚未恢复到暴露前水平。结果提示耳蜗血流下降在声损伤中起一定作用。

he effects of various noises at different intensities on cochlear bloodflow in guinea pigs were investigated with laser Doppler flowmeter, Afterexposure to l.5kHz,120dB pure tone or l.5kHz,110 or l20dB narrow bandnoise for 30 mins,the blood flow of the basaI turn of cochlea decreasedsignificantly,while after exposure to ll0dB pure tone or l00dB narrow bandnoise of l.5kHz for 30 mins the cochlear blood flow was not reduced. After noise exposure,the cochlear blood flow recovered gradually’ but didn’t re一 cover to normal yalue。The resuIt suggested that the reduction of cochlearbIood flow may play some roles in noise-induced acoustic injury。