大鼠脑室系统伸长细胞的顺行追踪研究

A ANTERGRADE TRACING STUDY OF THE TANYCYTES IN THE VENTRICULAR SYSTEM OF BRAIN IN RATS

用霍乱毒素亚单位与辣根过氧化物酶结合物（ＣＢ－ＨＲＰ）对脑室系统伸长细胞进行顺行追踪。结果在第三脑室壁腹侧２／３区，大量的伸长细胞发出浓密的突起，对称伸入下丘脑，甚至到达正中隆起腹侧软膜表面，其中部分突起可直接与下丘脑内的血管相接触。在侧脑室壁、第四脑室底和脊髓中央管也发现有伸长细胞，但数量远较第三脑室壁少。本实验表明，伸长细胞不仅存在于第三脑室壁，而且在脑室系统的其他部位也有分布。这一结果提示，伸长细胞的机能可能比以往的认识更复杂。

In order to observe the distributions of the tanycytes in the brain ventricular system of brain, 30%of the cholera toxin subunite B with horseradish peroxidase(CB-HRP)was injected into the lateral ventricle(LV)in 6 rats.This article reported the results of an anterograde tracing of the tanycytes.The basal processes of the tanycytes in the ventral two-third of the wall of third ventricle(III V)extended into the hypothalamus and even to the pia of the surface of the median eminence(ME).Some of the basal processes of the tanycytes in III V terminated in the vicinity of the capillaries in the hypothalamus.The tanycytes were also found in LV,fourth ventricle(IV V)and the central canal(CC)of the cervical spinal cord,but the number in above regions were much less than that in III V,The study indicated that the tanycytes existed not only in III V as reported previously,but also in LV,IV V and CC of the spinal cord.The results also suggested that the function pomted before of the tanycytes may be more complex than those in which the tanycytes were only considened to be related to the neuroendocrine regions.