针吸活检对肺癌诊断准确性的探讨

Study on diagnostic accuracy of aspiration biopsy of lung cancer

目的探讨针吸活检诊断肺癌的准确性和应用价值。方法CT引导下对肺部病变进行针吸活检术,针吸获得物制成涂片,对有组织块的标本进行常规石蜡包埋切片,所有标本均HE染色。收集有术后组织学对比的81例病例结果进行回顾性分析。结果穿刺涂片定性诊断准确率85.2%(69/81),穿刺组织切片为86.2%(56/65),两者结合为91.4%(74/81)。穿刺组织切片对肺癌分型诊断准确率为94.6%(53/56),比穿刺涂片的69.6%(48/69)高(P<0.01)。结论细针穿刺涂片与穿刺组织切片的诊断准确性均较高,后者对肺癌的分型有更高的应用价值。

Objective To study on the diagnostic accuracy and value of aspiration biopsy of lung cancer. Methods CTFNA biopsy was performed in lung-lesion cases. All the samples obtained were prepared into smears and the tissue blocks found were made into mini-tissue sections with paraffin embedded and HE stained. Then 81 cases with postoperative histologic diagnosis were collected and analysed retrospectively. Results The diagnosis sensitivity of CT-FNA smears and CT-FNA tissue sections were 85.2% （69/81） and 86.2% （56/65） respectively. The figure of overall sensitivity was 91.4% （74/81） when the two procedures were combined. In aspect of histological typing, the diagnostic accuracy of FNA tissue section （94. 60%） was significantly higher than of FNA smear （69.6%） （P〈0.01）. Conclusion The diagnostic accuracy of FNA smears and FNA tissue sections are high, whereas the latter is more valuable in histologic typing.