123例COPD患者抗生素相关性腹泻的临床分析

The Investigation of Antibiotic-Associated Diarrhea in 123 COPD Patients

目的:分析COPD患者抗生素相关性腹泻的发病率、发病因素,进一步探讨抗生素应用对腹泻严重程度的影响。方法:对我院呼吸内科病房5年内123例COPD患者合并抗生素相关性腹泻的临床资料进行回顾性分析。结果:抗生素使用时间≥7d,腹泻发生率明显升高,联合使用抗生素种类越多,腹泻发生率越高。结论:合理使用抗生素,严格控制广谱抗生素的使用,是预防控制医院感染抗生素相关性腹泻的关键措施。

Objective： To analyze the incidence and factors of antibiotic associated diarrhea （ AAD）, In addition, to investigate the effect of antibiotics on the degree of diarrhea. Method： To measure retrospectively the clinic findings of COPD patients complicated with AAD in respiratory department wards within 5 years. Result： The incidence of AAD was markedly high when the length of the antibiotic treatment was 37 days, nthe more kinds of the combined antibiotics the more incidence of the AAD. Conclusion： It was the key management of preventing and controlling AAD that appropriate antibiotic practice was aware and the broad - spectrum antibiotic was strictly controlled.