应变率成像评价扩张型心肌病患者左室心肌局域收缩及舒张功能的研究

Study on left ventricular regional systolic and diastolic function in patients with dilated cardiomyopathy by strain rate imaging

目的探讨应变率成像评价扩张型心肌病患者左心室局部收缩与舒张功能的价值。方法采集正常人20例和扩张型心肌病21例的动态组织多普勒图像后,分别测量其不同心肌节段在收缩期、舒张早期和舒张晚期的最大应变率,并进行对比分析。结果扩张型心肌病组收缩期应变率、舒张早期应变率及舒张晚期应变率明显低于正常组(P<0.05)。结论应变率成像可快速、无创地定量评价扩张型心肌病患者左室壁节段收缩及舒张功能,为临床评价心功能提供了又一有效方法。

Objective To assess the left ventricular（LV） regional systolic and diastolic function in patients with dilated cardiomyopathy（DCM） using strain rate imaging（SRI）.Methods Myocardial Doppler imaging of 20 healthy subjects and 21 DCM patients were collected, then the regional strain rate were measured in the apical, mid and basal segments in systolic, early diastolic and later diastolic period respectively. The parameters were analysed between the two groups. Results The parameters of systolic strain rate （s）, early diastolic strain rate（e） and later diastolic strain rate（a） of the DCM group were significantly lower than those of the normal group（ P 〈 0.05 ～ 0. 001）. Conclusion SRI is a rapid and noninvasive tool to quantitatively assess LV regional systolic and diastolic function in DCM patients, providing another useful modality for evaluating cardiac function.