老年性胃溃疡105例临床分析

Clinical analysis of 105 cases with gastric ulcer in elder patients

[目的]探讨老年性胃溃疡的发病机制及临床特征。[方法]对105例60岁以上的老年性胃溃疡(老年组)及281例60岁以下胃溃疡患者(非老年组)的临床和内窥镜资料进行回顾性比较分析。[结果]老年组在发病机制、溃疡位置及大小、临床症状、并发症等方面与非老年组均有明显的差异(P<0.01及P<0.05)。[结论]老年性胃溃疡发病机制以非甾体类抗炎药(NSAIDs)多见,症状不典型,并发症多,高位溃疡及巨大溃疡发生率高,应引起临床医师重视。

[Objective] To investigate the pathogenesis and the clinical features in elderly patients. [ Methods] The clinical and endoscopic data of 105 elderly patients above 60 years old with gastric ulcer（elderly group） were analyzed retrospectively and the results were compared with those of 281 young cases below 60 years old of gastric ulcer（under 60 years group）. [Results] The pathogenesis,position, size, clinical symptom and complication of the elderly patients are obviously different from the young patients（ P 〈 0.05 and P 〈 0.01）. [ Conclusion] For gastric ulcer in elderly patients , NSAIDs is a more important pathogeneic factor （ P 〈 0.01）, besides their clinical symptoms are not typical and usually they have many complications. The incidence of high ulcer and great ulcer increased apparently, which should arouse attention of doctors.