少年儿童单纯性肥胖症与血脂、脂肪肝、血压等指标关系的研究

Study on the Changes of Blood Lipids,Fatty Liver and Blood Pressure Among Simple Obesities

[目的]探讨少年儿童单纯性肥胖与血脂、脂肪肝、血压等因素的关系.[方法]采用2000年WHO以体重指数(BMI)≥23,第85百分位点作为肥胖界值点诊断的1977例少年儿童中,随机抽样74例为研究对象,男47例,女27例,年龄6～16岁.对照组随机选取体检合格学生31名.观测两组血脂,血压及肝脏B超等指标的变化.[结果]肥胖组检出29例脂肪肝,占39.19%;29例脂肪肝中24例儿童有高血压,占35.15%;血粘度异常的占29.73%.CHO、HDL-C、ApoA、GLU数据显示肥胖组与对照组差异无显著性(P＞0.05);TG、LDL-C、ApoB、Hs-CRP、ALT、INS数据显示两组差异有显著性(P＜0.01).[结论]少年儿童肥胖症主要与TG、LDL-c、Hs-CRP、ApoB、ALT、INS等呈正相关.

[Objective] To investigate the relationship between simple obesity and subhealth factors among the juveniles. [Methods] By using the 85th percentile of BMI （weight/height2） which was recommended by WHO as simple obesity among the juveniles between 6 and 18 years old, 74 juveniles were randomly sampled （male 47,female 27,ages between 6 and 16 years old） as the obesity group from 1977 students, while 31 physically eligible students were randomly sampled as the control group, Index changes of blood pressure, liver ultrasound were detected. [Results] Among 74 juveniles 29 （39. 19%） had fatty liver, 24 （35. 15%） of them with hypertension and the blood-viscosity of 22 （29.73% ） students was abnormal in the obesity group. There was no significant difference in the values of TC, HDL-C, ApoA and Glu between the obesity group and the control group （ P 〉0.05）, while the difference of the values of TG, LDL-C, ApoB, Hs-CRP and ALT was significant between the two groups（ P 〈0.01 ）. [Conclusion]The subhealth factors of simple obesity among the juveniles in Xiangtan city mainly include TG, LDL-C, ApoB, Hs-CRP ,ALT and INS.