钙调素信号系统在格列美脲促进糖原合成中的作用

Effect of calmodulin signal system on glycogen synthesis promoted by glimepiride

探讨格列美脲(GM)在促进正常大鼠骨骼肌糖原合成中对钙调素(CaM)信号的作用。结果显示在正常大鼠骨骼肌细胞中,GM能使CaM活性升高,CaM在GM促进胰岛素介导的骨骼肌糖原合成中起重要作用。

To investigate the effect of calmodulin （CaM） signal system on the glycogen synthesis in skeletal muscle cells from glimepiride （GM）-treated normal rats. The results showed that GM could activate CaM and CaM played a key role in GM inducing insulin-mediated glycogen synthesis.